J.ophthalmol.(Ukraine).2019;2:33-38.

http://doi.org/10.31288/oftalmolzh201923338

Received: 21 January 2019; Published-online: 24 April 2019


Results of vitreous surgery with 20% C3F8/air mixture for macular holes larger than 800 μm

A.A. Putienko, Dr Sc (Med)

Filatov Institute of Eye Disease and Tissue Therapy; Odessa (Ukraine) 

E-mail: alputienko@gmail.com

TO CITE THIS ARTICLE: Putienko AA. Results of vitreous surgery with 20% C3F8/air mixture for macular holes larger than 800 μm. J.ophthalmol.(Ukraine).2019;2:33-8. http://doi.org/10.31288/oftalmolzh201923338


Background: Vitreous surgery for large macular holes is still a challenge to the ophthalmologist.

Purpose: To assess the efficacy of the 20% C3F8/air mixture in the vitrectomy surgery for macular holes > 800 μm in diameter.

Materials and Methods: Twenty-two patients with macular hole of diameter ranging from 800 to 1,470 μm underwent vitrectomy with internal limiting membrane (ILM) peeling and tamponade with the 20% C3F8/air mixture.

Results: At 2 months after gas resorption, the macular hole was completely closed in 20 of the 22 eyes (90.9%). In addition, diameter of the hole dropped from 1,100 μm to 150 μm in one eye, and the hole did not close in another eye. Visual acuity improved significantly (χ2 = 13.15, p = 0.001) to 0.08-0.35. In 3 eyes, 12 eyes and 7 eyes, visual acuity improved to 0.05 – 0.08, 0.09 – 0.12, and 0.14 – 0.35, respectively.

Conclusion: The study demonstrated a high efficacy of the 20% C3F8/air mixture in the treatment of macular holes > 800 μm in diameter.

Keywords: macular hole larger than 800 μm; vitreous surgery; tamponade with the 20% C3F8/air mixture

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The authors certify that they have no conflicts of interest in the subject matter or materials discussed in this manuscript.