Infrared thermography of external ocular surface in patients with absolute glaucoma in transscleral cyclophotocoagulation: a pilot study

O. S. Zadorozhnyy, Cand Sc (Med), O. V. Guzun, Cand Sc (Med), A. Iu. Bratishko, T. B.  Kustryn I. O. Nasinnyk, A. R. Korol, Dr Sc (Med)

Filatov Institute of Eye Diseases and Tissue Therapy of NAMS of Ukraine; Odessa (Ukraine) 

E-mail: laserfilatova@gmail.com

Background: Changes in the temperature of external ocular surface in patients with absolute neovascular glaucoma (including the changes after transscleral contact cyclophotocoagulation with scleral compression (TCCSC)) are still to be investigated.

Purpose: To use infrared thermography (1) to investigate thermal patterns and to estimate the temperature of the external ocular surface in healthy individuals and (2) to compare these characteristics in the glaucomatous eyes versus intact fellow eyes of patients with absolute glaucoma undergoing treatment with 1064-nm TCCSC.

Materials and Methods: Twenty healthy volunteers (40 eyes) and 45 patients (90 eyes) with absolute glaucoma were under observation. All 130 eyes underwent visual acuity assessment, anterior eye photography, and infrared thermography of the external corneal surface. Each patient underwent three sessions of 1 064-nm TCCSC.

Results: In healthy subjects, mean external ocular surface temperature was 34.5 ± 0.7°C. For patients with absolute glaucoma, external corneal surface temperature at baseline was higher in intact fellow eyes than in glaucomatous eyes (34.3 ± 0.9°C versus 33.1 ± 0.8°С, P = 0.0008). In addition, increases in the temperature of external ocular surface were observed in the course of decrease in IOP after 1 064-nm TCCSC.

Conclusion: In patients with absolute glaucoma, infrared thermography found a marked thermal pattern asymmety between glaucomatous eyes and intact fellow eyes. In addition, increases in the temperature of external ocular surface in the course of decrease in IOP after 1064-nm TCCSC may be apparently attributed to improved ocular blood flow and inflammatory response of the ciliary body to laser photocoagulation.

Keywords: infrared thermography, temperature of external ocular surface, absolute glaucoma


  1. Tan JH, Ng EYK, Rajendra Acharya U, Chee C. Infrared thermography on ocular surface temperature: A review. Infrared Phys Technol. 2009;52(4):97–108
  2. Anatychuk LI, Pasyechnikova NV, Zadorozhnyy OS, Nazaretian RE, Myrnenko VV, Kobylyanskyi RR, Gavryliuk NV. [Device for intraocular thermometry and temperature patterns in different portions of the rabbit eye (experimental study)]. Zhurnal NAMN Ukrainy. 2016; 22(1):103–8. Russian
  3. Schwartz B. Environmental temperature and the ocular temperature gradient. Arch Ophthalmol. 1965;74:237–43
    Crossref   Pubmed
  4. Auker CR, Parver LM, Doyle S, et al. Choroidal blood flow. I. Ocular tissue temperature as a measure of flow. Arch Ophthalmol. 1982 Aug;100(8):1323–6
    Crossref   Pubmed
  5. Havens SJ, Gulati V. Neovascular Glaucoma. Dev Ophthalmol. 2016. 55:196-204.
    Crossref   Pubmed
  6. Chechin PP, Repiakh VS, Guzun OV. [Transscleral laser cyclophotocoagulation in the treatment for refractory glaucoma]. Tavricheskii medico-biologicheskii vestnik. 2012;15(3):200–2 Russian
  7. Zadorozhnyy O, Korol A, Nevska A, Kustryn T, Pasyechnikova N. Ciliary body imaging with transpalpebral near-infrared transillumination – a pilot study. Klinika oczna. 2016;3:184–6
  8. Galassi F, Giambene B, Corvi A, Falaschi G. Evaluation of ocular surface temperature and retrobulbar haemodynamics by infrared thermography and colour Doppler imaging in patients with glaucoma. Br J Ophthalmol. 2007;91(7):878–81
    Crossref   Pubmed
  9. Sodi A, Giambene B, Falaschi G, et al. Ocular surface temperature in central retinal vein occlusion: preliminary data. Eur J Ophthalmol. 2007 Sep-Oct;17(5):755-9
    Crossref   Pubmed
  10. Morgan PB, Smyth JV, Tullo AB, Efron N.  Ocular temperature in carotid artery stenosis. Optom Vis Sci. 1999;76(12):850–4
    Crossref   Pubmed
  11. Galassi F, Giambene B, Corvi A, et al. Retrobulbar hemodynamics and corneal surface temperature in glaucoma surgery. Int Ophthalmol. 2008;28(6):399–40
    Crossref   Pubmed
  12. Fujishima H, Toda I, Yagi Y, Tsubota K. Quantitative evaluation of postsurgical inflammation by infrared radiation thermometer and laser flare-cell meter.  J Cataract Refract Surg. 1994 Jul;20(4):451–4
    Crossref   Pubmed
  13. Toris CB, Camras CB, Yablonski ME. Acute versus chronic effects of brimonidine on aqueous humor dynamics in ocular hypertensive patients. Am J Ophthalmol. 1999 Jul;128(1):8–14
    Crossref   Pubmed