J.ophthalmol.(Ukraine).2018;2:7-10.

https://doi.org/10.31288/oftalmolzh/2018/2/710

Pathogenetic treatment for neurotrophic keratopathy 
T. B. Gaidamaka, Dr. Sc. (Med.); T. A. Veliksar, Postgraduate Student; G. I. Drozhzhyna, Dr. Sc. (Med.); T. M. Serebrina, Cand. Sc. (Med.) 
Filatov Institute of Eye Diseases and Tissue Therapy; 
Odessa (Ukraine)
Introduction. Continuous soft contact lens (SCL) wearing can result in development of neurotrophic keratopathy. Treatment of this pathology is long-term and, in general, symptomatic: tear-substitute, epithelizing, vitaminous, antibacterial, anti-inflammatory therapy.
Purpose. To improve a correction method for metabolic alterations in corneal tissues in continuous-SCL-wear-associated neurotrophic keratopathy through using transorbital electrophoresis with 1% thiotriazoline.  
Material and Methods. We developed a method of treatment for neurotrophic keratopathy which includes a 10 day course of daily transorbital electrophoresis with 1% thiotriazoline as a part of complex therapy. We applied for approval of Author's certificate (application No U 201710621 dated 01 November 2017).
Results. Clinical cases of treatment of stage 1 neurotrophic keratopathy are reported.   
Conclusion. The proposed treatment enables in a short term to significantly decrease pathological changes in corneal tissues in stage 1 neurotrophic keratopathy, to increase comfort in the eyes, to prevent severe complications of neurotrophic keratopathy and soft contact lens wearing. 
Key-words: neurotrophic keratopathy, contact lenses, thiotriazoline, electrophoresis
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