Results of phosphene electrostimulation treatment of patients with primary open-angle glaucoma 

V. A. Putienko

V.S. Ponomarchuk, Dr Sc (Med), Prof. 

Filatov Institute of Eye Diseases and Tissue Therapy, NAMS of Ukraine

Odessa, Ukraine

E-mail: alputienko@ya.ru

The purpose was to assess the efficacy of phosphene electrostimulation in patients with stage II and III of primary open-angle glaucoma with compensated IOP.

Material and Methods. We followed up 26 patients (31 eyes) with drug-compensated primary open-angle glaucoma (POAG). 16 eyes with stage II glaucoma comprised the first group. The second group consisted of 15 eyes with stage III glaucoma. Treatment included 10 PES standard sessions. Each session lasted 10 minutes. Current dose was selected in every particular case in regard to initial зhosphene threshold of electric sensitivity (PTES) level. Treatment efficacy was assessed according to rate changes in PTES, CFPD in «1.5» and «3» modes and according to changes in computer perimetry data.

Results. FES in stage II POAG patients enabled to improve retinal light perception by 19.3% and to increase electrical sensitivity of visual analyzer (phosphene threshold increased by 14.4%). In stage III patients, light perception increased by 14.8%,  phosphene threshold of electrical sensitivity increased by 15.2%, and phosphene electrical lability in modes 1.5 and 3.0 increased by 13.5% and 21.1%, respectively, which made it possible to recommend the treatment for this category of patients. 

Key words: primary open-angle glaucoma, phosphene electrical stimulation, phosphene threshold, critical frequency of phosphene disappearance



1.Alexeev VN, Levko MA, Al–Gifari AM. [Comparison of effects of Xalatan, Travatan and Tafluprost usage in treatment of primary glaucoma]. Klinicheskaia Oftalmologiia. 2008;9(3):108-10. Russian. 

2.Bobr TV, Rozhko JI. [Functional activity of the retina in compensated glaucoma]. ARSmedica. 2011;16(52):52–5. Russian. 

3.Drozhenko V.S. The influence of the modificate phosphenelectrical stimulation on the visual functions of patients with partial optic nerve atrophy. Thesis for a candidate’s degree. Odessa; 2002. 158 p. Russian

4.Zavgorodniaia  NG, Pasechnikova  NV. [Primary glaucoma: A new look at an old problem]. Zaporizhzhia: Orbita-YUG; 2010. p. 192. Russian

5.Ponomarchuk VS, Degtyarenko TV, Chaura AG et al. [Mechanisms responsible for the curative effect of phosphen-electrostimulation]. Neurophysiology. 1998;30:431. doi:10.1007/BF03027698

6.Strakhov VV, Alekseev VV. [The pathophysiology of a primary glaucoma — "all or anything"]. Glaucoma.2009;2:10-2. Russian. 

7.Chaura AG. [Physiological mechanism of realization of visual analyzer electrical stimulation effect]. Thesis for Cand. Of Sc. (Biol.) Odessa; 2009. 170 p. Ukrainian.

8.Shevchenko ON, Yusupov RG, Muldashev ER. [The effectiveness of the combined use of transcutaneous electrical stimulation and combination therapy in the treatment of primary compensated glaucoma]. Proceedings of All-Russian scientific practical conference “Glaucoma Millennium: Results and Prospects”. Moscow; 1999. 336-8. Russian.   

9.Kerrigan Baumrind L, Quigley H, Pease M et al. Number of ganglion cells in glaucoma eyes compared with threshold visual field tests in the same persons.  Invest Ophthalmol Vis Sci. 2000;41:741–8.