J.ophthalmol.(Ukraine).2015;5:13-17.

https://doi.org/10.31288/oftalmolzh201551317

Use of keratoxenoimplant for therapeutic and therapeutic-and-tectonic keratoplasty in severe ocular burns and corneal ulcerations of various etiologies

N.V. Pasyechnikova1, Corr. Member of the NAMS of Ukraine, Dr. Sc. (Med), Prof., S.A. Iakymenko1, Dr. Sc. (Med), Prof., M.V. Turchyn2, Cand. Sc. (Med), Ass. Prof., O.I. Buznyk1, Cand. Sc. (Med), P.O. Kostenko1, Cand. Sc. (Med)

1 Filatov Institute of Eye Diseases and Tissue Therapy,

2 Horbachevsky Ternopil State Medical University

E-mail: piter1812@gmail.com

Background: The acute shortage of human donor corneas for transplantation has emerged, setting ophthalmologists a task of searching for new graft materials for use in keratoplasty.

Purpose: To investigate the possibility of using the keratoxenoimplant for therapeutic or therapeutic-and-tectonic keratoplasty in ocular burns or ulcerative sequelae of corneal inflammatory diseases.

Materials and Methods: A clinical study of the use of the keratoxenoimplant was performed in 69 eyes (60 patients) with ocular burns or ulcerative sequelae of corneal inflammatory diseases.

Results: In all eyes of the study, the keratoxenoimplant was found to facilitate the preservation of the globe and light perception. In some patients, following a number of rehabilitative-and-reconstructive procedures, we managed to implant the keratoprosthesis and to restore sight (in some cases to the visual acuity of 0.5). 

Conclusion: The results provide the basis for recommendation of the keratoxenoimplant for wide use if human donor material is not easily available.

Keywords: keratoxenoimplant, ocular burn, corneal inflammatory diseases.

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