http://doi.org/10.31288/oftalmolzh201026466

ULTRASTRUCTURAL CHANGES OF THE RAT OPTIC NERVE ELEMENTS IN DYNAMICS AFTER THE INFLUENCE OF METHANOL

Dumbrova N. E., Molchanyuk N. I.

Odessa, Ukraine

The changes of the rat optic nerve were investigated in dynamics (1-14 days) photooptically and electron-micro-scopically after introduction of methyl alcogol in the dose of 0,75 g/kg of the body mass. It is established that nerve fibers react in the greatest degree to the action applied: on the 1-7 days is noted dropsy of axoplasma, exfoliations of myelin membranes, swelling of the mitochondria. On the 14th day sign of the swelling axoplasma reduced hovewer is noted deformation of the myelin membranes. In the glial cell is noted both partial destruction and restoration of the normal structure. The study will be continued.

 

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