Офтальмол. журн. — 2020. — № 4. — С. 28-32.

http://doi.org/10.31288/oftalmolzh202042832


УДК  617.751.6:617.753.5:612.087.1:617.713

A New Parameter in The Etiology of Hyperopic Anisometropic Amblyopia: Corneal Densitometry 

Erdinç Bozkurt, Assist. Prof.; Ersin Muhafız, Assist. Prof.; Hayrunisa Bekis Bozkurt , Assist. Prof.; Serif Nizamoğlu, Asistant

Kafkas University, Faculty of Medicine; Kars (Turkey)

E-mail:  drerdincbozkurt@hotmail.com

КАКЦИТИРОВАТЬErdinç Bozkurt. A New Parameter in The Etiology of Hyperopic Anisometropic Amblyopia: Corneal Densitometry. Erdinç Bozkurt, ErsinMuhafız, HayrunisaBekisBozkurt, SerifNizamoğlu. // Офтальмол. журн. – 2020. – № 4. – С. 28-32. http://doi.org/10.31288/oftalmolzh202042832


Objectives. To evaluate the anterior segment parameters and densitometric values of cornea and lens in children with anisohipermetropic amblyopia by corneal topography and optical biometry devices.

Design. Prospective cross sectional study.

Participants. Ambliopic and fellow eyes of 42 children with anisohipermetropic amblyopia (19 males, 23 females, mean age 9.98±3.88 years) and right eyes of 44 healty children from pediatric outpatient (22 males, 22 females, mean age 9.41±4.1 years)  were included in this study.

Methods. All patients were evaluated with sirius topography and optical biometry. Visual acuities, spherical refractive values, mean keratometric values, axial lengths, central corneal thickness, corneal volume, anterior chamber depth, anterior chamber volume, iridocorneal angle, pupil diameter, white to white, cornea densitometry and lens densitometry of amblyopic eyes, fellow eyes and healthy eyes were compared.

Results. Visual acuity was 0.332±0.024, 0.0132±0.0058, 0.001 (LogMAR) for amblyopic, fellow and healthy eyes respectively (p = 0.003), spherical refractive 3.79±2.52, 1.33±1.29 and 0.98±0.39 respectively (p = 0.025). ICA and central corneal densitometry were found lower in amblyopic eyes than in fellow and healty eyes among sirius corneal topography parameters (p value 0.041, 0.001). There was no significant difference between groups in terms of optical biometry parameters except axial length.

Conclusion. In our study, we found that there were significant differences in iridocorneal angle, central corneal densitometry between groups. We think that it may be an important parameter in corneal density except for spherical equivalent and axial length in the etiology of hyperopic anisometropic amblyopia.

Keywords: аnisohipermetropic amblyopia, anterior segment parameters, cornea and lens densitometry, corneal topography, optical biometry

 

References

1.Holmes JM, Clarke MP. Amblyopia. Lancet. 2006; 22: 1343-51.

2.Hatt S, Antonio-Santos A, Powell C et al. Interventions for stimulus deprivation amblyopia. Cochrane Database Syst Rev. 2006; 19: 3. 

3.Flom MC. Neumaier R.W. Prevalence of Amblyopia. Public Health Reports 1966; 81: 329-341.

4.Caca I, Cingu AK, Sahin A et al. Amblyopia and refractive errors among school-aged children with low socioeconomic status in southeastern Turkey. J Pediatr Ophthalmol Strabismus 2013; 50: 37-43.

5.Von Noorden GK. Amblyopia. In: Lampert R, editor. Binocular vision and ocular motility. 6th ed. St Louis: CV Mosby Company, 2002. p 246-97.

6.Bayhan HA, Aslan Bayhan S, Muhafiz E, et al. Comparison of anterior segment parameters with optical low coherence reflectometer and combined scheimpflug-placido disk topographer. Glo-Kat 2013;8:78-82.

7.Palamar M, Degirmenci C, Biler ED, et al. Evaluation of the anatomic and refractive differences in hyperopic anisometropia. Int Ophthalmol 2016; 36(6): 881-6.

8.Davidson S, Quinn GE. The impact of pediatric vision disorders in adulthood. Pediatrics 2011; 127(2): 334–9.

9.Koçak G, Duranoğlu Y. Amblyopia and Treatment. Turk J Ophthalmol 2014; 44(3): 228–36.  

10.Holmstrom M, el Azazi M, Kugelberg U. Ophthalmological long-term follow up of preterm infants: a population based, prospective study of the refraction and its development. Br J Ophthalmol 1998; 82: 1265-71.

11.Weakley DR Jr. The association between nonstrabismic anisometropia, amblyopia, and subnormal binocularity. Ophthalmol 2001; 108: 163-71.

12.Abrahamsson M, Sjostrand J. Natural history of infantile anisometropia. Br J Ophthalmol 1996; 80:860-3.

13.Uretmen O, Pamukcu K, Kose S, et al. Oculometric features of hyperopia in children with accommodative refractive esotropia. Acta Ophthalmol Scand 2003; 81: 260-3.

14.Dervişoğlu S, Gürlü V, Erda N. Factors Causing Difference in Refractive Defects Between Two Eyes in Anisometropic Amblyopia Cases Anizometropi. Balkan Medical Journal 2006; 2006(2): 65-69

15.Wang BZ, Taranath D. A comparison between the amblyopic eye and normal fellow eye ocular architecture in children with hyperopic anisometropic amblyopia. J AAPOS 2012; 16(5): 428-30.

16.Yuksel N, Yuksel E, Ozer MD. Evaluation of anterior segment parameters using the Pentacam in hyperopic anisometropic amblyopic and normal eyes. J AAPOS 2014; 18(3): 248-50.

17.Demircan S, Gokce G, Yuvaci I et al. The assessment of anterior and posterior ocular structures in hyperopic anisometropic amblyopia. Med Sci Monit 2015; 21: 1181-8.

18.Bernardo L, Isaac R, Renato A Jr. Corneal Densitometry in Keratoconus. Cornea 2014; 33 (12): 1282–1286

19.Ahmed OM, Fares U, Al-Aqaba MA, et al. Corneal Densitometry as an Indicator of Corneal Health. Ophthalmol 2012; 119(3): 501–508.

20.Weiner X, Baumeister M, Kohnen T, et al. Repeatability of lens densitometry using Scheimpflug imaging. Journal of Cataract & Refractive Surgery 2014; 40(5): 756–763.

21.Kashima K, Trus BL, Unser M, et al. Aging studies on normal lens using the Scheimpflug slit-lamp camera. Invest. Ophthalmol. Vis. Sci 1993; 34(1): 263-269.

22.Ortiz D, Alió JL, Ruiz-Colechá J, et al. Grading nuclear cataract opacity by densitometry and objective optical analysis. Journal of Cataract & Refractive Surgery 2008; 34(8): 1345–1352.

23.Huang J, Savini G, Li J, et al Evaluation of a new optical biometry device for measurements of ocular components and its comparison with IOLMaster. Br J Ophthalmol 2014; 98: 1277-1281.

24.Satou T, Niida T, Ito M. Biometry: a tool for the detection of amblyopia risk factor in children. Graefes Arch Clin Exp Ophthalmol 2019; 257(9): 2049-2056. 

25.Tekin K, Cankurtaran V, Inanc M, et al. Effect of myopic anisometropia on anterior and posterior ocular segment parameters. Int Ophthalmol. 2017; 37(2): 377-384.

 

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. The authors did not receive any financial support from any public or private source.

Received 27.03.2020