Received: 30.07.2022; Accepted: 03.08.2022; Published on-line: 27.10.2022
Photobiomodulation therapy in ophthalmology
O. S. Zadorozhnyy, A. R. Korol, I. O. Nasinnyk, T. B. Kustryn, A. O. Nevska; N. V. Pasyechnikova
SI "The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine";
TO CITE THIS ARTICLE: Zadorozhnyy OS, Korol AR., Nasinnyk IO, Kustryn TB, Nevska AO, Pasyechnikova NV. Photobiomodulation therapy in ophthalmology. J.ophthalmol.(Ukraine).2022;5:47-53. http://doi.org/10.31288/oftalmolzh202254753
Photobiomodulation (PBM) therapy is a form of light therapy that utilizes non-ionizing forms of light sources in the far-red to near-infrared spectrum to produce non-thermal photochemical reactions in different biological structures. The paper reviews the experience of implementing (a) PBM in different fields of medicine (e.g., ophthalmology) and (b) the known mechanisms of PBM-induced effects on cells and tissues.
Keywords: photobiomodulation therapy, far-red to near-infrared light spectrum, retina, mitochondria
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Corresponding Author: O. S. Zadorozhnyy, e-mail: email@example.com
Authour Contribution: The authors acknowledge the following contributions: Conception and design of the study: NP; acquisition of literature data and analysis: OZ, TK, IN, AN, AK; drafting the manuscript: OZ. All authors have read and approved the final version of the manuscript.
Sources of Support: This research has not received any specific grant from funding agencies in the public, commercial or non-profit sectors.
Conflict of Interest Statement: All authors have read the journal's author agreement and the policy of disclosure of potential conflicts of interest. The authors have no potential conflicts of interest.
Abbreviations. PMM, photobiomodulation; LLLT, low-level laser (or light) therapy; FR/NIR, far-red/near-infrared light; ATP, adenosine triphosphate; CcO, cytochrome C oxidase; NO, nitric oxide; AMD, age-related macular degeneration; CI-DME, center-involved diabetic macular edema; LED, light emitting diode; BCVA, best corrected visual acuity; PERG, pattern electroretinography.