J.ophthalmol.(Ukraine).2021;5:28-34.

http://doi.org/10.31288/oftalmolzh202152834

Received: 15 July 2021; Published on-line: 23 October 2021


Ocular hemodynamics in patients with rhegmatogenous retinal detachment complicated by choroidal detachment

N. I. Khramenko, M. M. Umanets, Z. A. Rozanova, G. V. Levytska

SI "The Filatov Institute of Eye Diseases and Tissue Therapy of the NAMS of Ukraine"; Odesa (Ukraine)

E-mail:  khramenkon@gmail.com

TO CITE THIS ARTICLE: Khramenko NI, Umanets MM, Rozanova ZA, Levytska GV. Ocular hemodynamics in patients with rhegmatogenous retinal detachment complicated by choroidal detachment. J.ophthalmol.(Ukraine).2021;5:28-34.  http://doi.org/10.31288/oftalmolzh202152834

 

Background: The occurrence of choroidal detachment (CD) in eyes with primary rhegmatogenous retinal detachment (RRD) is relatively uncommon (2%-8.6%). We hypothesized that significant disturbances in blood supply to the retina are a mechanism of the pathogenesis of RRD complicated by CD, which prompted us to study ocular hemodynamics in relevant patients.

Purpose: To assess preoperative hemodynamics of the affected eye and fellow eye in patients with RRD complicated by CD.

Material and Methods: We preoperatively examined the affected eye and fellow eye and assessed their hemodynamics in two groups of 11 patients each (the uncomplicated RRD group and the RRD complicated by CD group) which were similar with regard to age, time from the onset of RRD and ocular comorbidity.

Results: Volumetric ocular pulse blood filling (OPBF) values in the affected eye and fellow eye of the latter group were 68.7% and 40%, respectively, lower, whereas of the former group, 33.3% and 27%, respectively, lower, than in age-matched normals. In addition, volumetric ocular pulse blood filling positively correlated with intraocular pressure (r=0.5; p < 0.05) in patients of both groups. This indicated that there is a significant ischemic process in the eye with RRD, which is aggravated in the presence of CD.

Keywords: rhegmatogenous retinal detachment, choroidal detachment, ophthalmic rheography,  ocular pulse blood filling, intraocular pressure

 

References 

1.Foos RY, Wheeler NC. Vitreoretinal juncture. Synchysis senilis and posterior vitreous detachment. Ophthalmology. 1982 Dec;89(12):1502-12.

Crossref

2.Jaffe N.S. Complications of acute posterior vitreous detachment //Arch Ophthalmol. – 1968. – Vol.79. – P.568–571. Jaffe NS. Complications of acute posterior vitreous detachment. Arch Ophthalmol. 1968 May;79(5):568-71.

Crossref  PubMed

3.Tasman WS. Posterior vitreous detachment and peripheral retinal breaks. Trans Am Acad Ophthalmol Otolaryngol. Mar-Apr 1968;72(2):217-24.

4.Lindner B. Acute posterior vitreous detachment and its retinal complications. Acta Ophthalmol. 1966;87(suppl):1–108.

5.Sharma T, Gopal L, Reddy RK, et al. Primary vitrectomy for combined rhegmatogenous retinal detachment and choroidal detachment with or without oral corticosteroids: a pilot study. Retina. Feb-Mar 2005;25(2):152-7.

Crossref  PubMed

6.Yu Y, An M, Mo B, et al. Risk factors for choroidal detachment following rhegmatogenous retinal detachment in a Chinese population. BMC Ophthalmol.  2016 Aug 9;16:140.

Crossref  PubMed

7.Gu YH,  Ke GJ,  Wang L, et al. Risk factors of rhegmatogenous retinal detachment associated with choroidal detachment in Chinese patients. Int J Ophthalmol. 2016 Jul 18;9(7):989-93.

Crossref  

8.Kang JH, Kyung AP, Woo JS, Se WK. Macular Hole as a Risk Factor of Choroidal Detachment in Rhegmatogenous Retinal Detachment. Korean J Ophthalmol. 2008 Jun; 22(2): 100–3.

Crossref  PubMed

9.Li Z, Li Y, Huang X, et al. Quantitative analysis of rhegmatogenous retinal detachment associated with choroidal detachment in Chinese using UBM. Retina. Nov-Dec 2012;32(10):2020-5.

Crossref  PubMed

10.Jarrett 2nd WH. Rhegmatogenous retinal detachment complicated by severe intraocular inflammation, hypotony, and choroidal detachment. Trans Am Ophthalmol Soc. 1981; 79: 664-83.

11.de Smedt S, Sullivan P. Massive choroidal detachment masking overlying primary rhegmatogenous retinal detachment: A case series. Bull Soc Belge Ophtalmol. 2001;(282):51-5.

12.Sharma T, Gopal L, Badrinath SS. Primary vitrectomy for rhegmatogenous retinal detachment associated with choroidal detachment. Ophthalmology. 1998 Dec;105(12):2282–5.

Crossref

13.Ghoraba HH. Primary vitrectomy for the management of rhegmatogenous retinal detachment associated with choroidal detachment. Graefes Arch Clin Exp Ophthalmol. 2001 Oct;239(10):733-6.

Crossref  PubMed

14.Dai Y, Wu Z, Sheng H, et al. Identification of inflammatory mediators in patients with rhegmatogenous retinal detachment associated with choroidal detachment. Mol Vis. 2015 Apr 10;21:417-27.

15.Cook B, Lewis GP, Fisher SK, Adler R. Apoptotic photoreceptor degeneration in experimental retinal detachment. Invest Ophthalmol Vis Sci. 1995 May;36(6):990-6. 

16.Zacks DN, Hänninen V, Pantcheva M, et al. Caspase activation in an experimental model of retinal detachment. Invest Ophthalmol Vis Sci. – 2003 Mar;44(3):1262-7.

Crossref  PubMed

17.Trichonas G, Murakami Y,  Thanos A, et al. Receptor interacting protein kinases mediate retinal detachment – induced photoreceptor necrosis and compensate for inhibition of apoptosis. Proc Natl Acad Sci USA. 2010 Dec 14;107(50):21695-700.

Crossref  PubMed

18.Suzuki Y, Adachi K, Takahashi S, et al. Oxidative Stress in the Vitreous Fluid with Rhegmatogenous Retinal Detachment. J Clin Exp Ophthalmol. – 2017; 6:5.

Crossref

19.Yoshimura T, Sonoda KH, Sugahara M, et al. Comprehensive analysis of inflammatory immune mediators in vitreoretinal diseases. PLoS One. 2009; 4(12):e8158.

Crossref  PubMed

20.Xu C, Wu J, Feng C. Changes in the postoperative foveal avascular zone in patients with rhegmatogenous retinal detachment associated with choroidal detachment. Int Ophthalmol. 2020 Oct;40(10):2535-43.

Crossref  PubMed

21.Аlibet Yassine, Ponomarchuk VS, Levytska GV, Khramenko NI. Comparing bioelectrical activity of the peripheral retina among myopic patients operated for rhegmatogenous retinal detachment complicated by choroidal detachment. J Ophthalmol (Ukraine). 2018;3:41–51.

Crossref 

22.Alibet Yassine, Ponomarchuk VS, Khramenko NI, Levytska GV. Comparing bioelectrical activity of the central retina among myopic patients operated for rhegmatogenous retinal detachment complicated by choroidal detachment. J Ophthalmol (Ukraine). 2018;4:7–25.

Crossref

23.Dobbie JG. A study of the intraocular fluid dynamics in retinal detachment. Arch Ophthalmol. 1963 Feb;69:159-64.

Crossref  PubMed

24.Yoshioka H, Endo Y. Clinical observations on ocular tension in cases of retinal detachment. Rinsho Ganka. 1966;20:193–201.

25.Swan KG, Christensen L, Weisel JT. Choroidal detachment in the surgical treatment of retinal separation. AMA Arch Ophthalmol. 1956 Feb;55(2):240-5.

Crossref  PubMed

 

Conflict of Interest:

The authors declare that there are no conflicts of interest that would influence their opinion on the subject matter or materials described and discussed in this manuscript.