Disability due to ocular complications of diabetes mellitus in Ukraine
I.S. Alifanov,1 Teaching Assistant; V.N. Sakovych,1 Dr Sc (Med), Prof; T.O. Alifanova,2 Cand Sc (Med), Senior Research Fellow
1 Dnipropetrovsk Medical Academy, Ministry of Health of Ukraine; Dnipro (Ukraine)
2 Ukrainian State Research Institute for Medical and Social Problems of Disability of Ministry of Health of Ukraine; Dnipro (Ukraine)
Background: Diabetes mellitus (DM) is a global epidemic. According to reports from the WHO, DM patients have a significantly shorter life span compared to general population, and DM is among the three diseases with the highest risk of disability and mortality.
Purpose: To investigate the rates of disability due to ocular complications of DM in Ukraine for the time period from 2004 to 2018.
Results: The prevalence of DM in Ukraine was increasing during this period. The annual prevalence of individuals certified as having a DM-induced disability for the first time was relatively stable during 2004 through 2018 and was 1.5 per 10,000 of adult population in 2018. The annual prevalence of individuals certified as having a diabetic retinopathy (DR)-induced visual disability for the first time per 10,000 of adult population was 0.19 in 2018, and varied substantially during the period from 2004 to 2018, with a minimum of 0.13 in 2006 and 2015, maximal values of 0.22 and 0.20 in 2010 and 2015, respectively, and a general tendency to increase. During the period, changes in the prevalence of DR-induced disability varied among Ukrainian regions differing in geographical aspects. The proportion of blind and visually impaired (i.e., severely and moderately disabled, respectively) among individuals certified as having a DR-induced visual disability was higher than that among total individuals certified as having a visual disability for the first time; this indicates that the pathology is severe. The level of accumulated disability due to ophthalmic diabetes in Ukraine increased almost 2.5-fold during the last 15 years.
Keywords: diabetes mellitus, diabetic retinopathy, blindness, disability
1.International Diabetes Federation. IDF Diabetes Atlas. 8th Ed. Brussels: International Diabetes Federation; 2017. Available at: http://www.diabetesatlas.org.
2.International Council Of Ophthalmology. ICO Guidelines for Diabetic Eye Care (2017). Available at: http://www.icoph.org/downloads/ICOGuidelinesforDiabeticEyeCare.pdf
3.Zborovska OV, Pilkevich TS, Kuryltsiv NB, Samoluk NA. Proliferative diabetic retinopathy in unsuspected diabetes mellitus: a case report. J.ophthalmol. (Ukraine). 2019;2:67-9.
4.Emerging Risk Factors Collaboration, Sarwar N, Gao P, Sechasai SR, Golin R, Kaptoge S, et al. Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies. Lancet. 2010 Jun 26;375(9733):2215-22.
5.Pasyechnikova NV, Naumenko VA, Vit VV, Ivanitskaya EV, Pilkevich TS. [Structural changes of the retina, erythropoietin concentration in the vitreous body and peripheral blood in streptozotocin-induced diabetic rats in experiment (intermediate result)]. J Ophthalmol (Ukraine). 2014;3:69-75. Ukrainian.
6.Sakovich VN, Ahmad Abed Al Raheem Abdallah Aqrabawi. [The influence of nicotinamide and preparations containing it on the level of oxidated and reduced forms of nicotinamide coenzymes in the retina of rats with streptosotocine diabetes]. J Ophthalmol (Ukraine). 2013;1:57-61. Ukrainian.
7.Bourne RR, Stevens GA, White RA, Smith JL, et al. Causes of vision loss worldwide, 1990-2010: a systematic analysis. Lancet Glob Health. 2013 Dec;1(6):e339-49.
8.Bezditko PA, Gorbachova EV. [Epidemiology and prevalence of diabetes mellitus and diabetic retinopathy]. International journal of endocrinology. 2006;4(6). Russian. Available at: http://www.mif-ua.com/archive/article/2062.
9.Cavan D, Makaroff L, da Rocha Fernandes J, Sylvanowicz M, et al. The Diabetic Retinopathy Barometer Study: Global perspectives on access to and experiences of diabetic retinopathy screening and treatment. Diabetes Res Clin Pract. 2017 Jul;129:16-24.
10.Rykov SO, Alifanova TO, Alifanov IS. [Disability due to ocular complications of diabetes mellitus in Ukraine]. J Ophthalmol (Ukraine). 2006;3:126-8. Ukrainian.
The authors certify that they have no conflicts of interest in the subject matter or materials discussed in this manuscript.