J.ophthalmol.(Ukraine).2018;5:56-59.

https://doi.org/10.31288/oftalmolzh201855659

Received: 29 June 2018; Published on-line: 26 October 2018


Relationship between severity of HIV infection and ocular pathology in patients with pulmonary tuberculosis

I.N.Voronova1, V.M. Khokkanen2, S.I. Sanaeva1, M.V. Zhemkova1

1 St Petersburg City Tuberculosis Dispensary; St. Petersburg (Russia)

2 Mechnikov North-West State Medical University; St. Petersburg (Russia)

E-mail: anirilas@yandex.ru       

TO CITE THIS ARTICLE: Voronova IN, Khokkanen VM, Sanaeva SI, Zhemkova MV. Relationship between severity of HIV infection and ocular pathology in patients with pulmonary tuberculosis. J.ophthalmol.(Ukraine).2018;5:56-59. https://doi.org/10.31288/oftalmolzh201855659 

    

Background: Pulmonary tuberculosis most commonly develops and often becomes generalized among HIV-infected patients. HIV-positive individuals present extra-pulmonary forms of tuberculosis twice as often as HIV-negative individuals.

Purpose: To determine the frequency of ocular pathology and the relationship between ocular pathology and CD4 cell count in HIV-positive patients with tuberculosis.

Materials and Methods: Three thousand and eighty four patients with pulmonary tuberculosis including 320 (10.4%) patients co-infected with HIV underwent examination at the City Tuberculosis Dispensary between 2014 and 2016.

Results: Allergic or toxic retinal vasculitides and peripheral focal chorioretinitis of tuberculous etiology in either active or inactive inflammatory phase were most common ocular disorders among HIV-positive patients with marked immune deficiency. In these patients, median CD4 cell count was ≤200-300 cells/mm3 compared to the norm of 1600 cells/mm3.

Keywords: HIV, ocular tuberculosis, CD4 cells

 

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