J.ophthalmol.(Ukraine).2018;2:56-59.

https://doi.org/10.31288/oftalmolzh/2018/2/5659

A case of successful using a stromal corneal transplant for therapeutic keratoplasty in a patient with herpetic keratitis

E. V. Sereda, a junior research fellow; G. I. Drozhzhyna, Dr. Sc. (Med.), Prof.; T. B. Gaidamaka, Dr. Sc. (Med.)

SI “Filatov Institute of Eye Diseases and Tissue Therapy of NAMS of Ukraine”; Odessa (Ukraine) 

E-mail: evsereda08@gmail.com

Introduction.  Herpes virus infection is a cause of inflammatory corneal diseases in 20-57 % of cases. To date, due to the lack and high cost of donor material in Ukraine, approbation of new material for keratoplasty is of great relevance. 

Purpose. To report a case of successful using a stromal corneal transplant for therapeytic keratoplasty in a patient with herpitic keratitis.  

Material and Methods. Visual acuity testing, standard ophthalmic examination, microbiology study. 

Results. Using lyophilized stromal layers made it possible to prevent corneal perforation in a patient with herpetic keratitis. Early operative intervention made it possible to preserve visual function and to avoid severe complications. 

Conclusions. If urgent keratoplasty is required and keratobioimplant is not available/affordable, lyophilized stromal layers of the cornea with the Descemet's membrane can serve as an alternative material for therapeutic tectonic keratoplasty and can prevent development of severe keratitis complications including descemetocele, corneal perforation etc.

Key-words: herpes, corneal ulcer, therapeutic keratoplasty, corneal stroma

Reference
 
  1. Kasparov AA, Vorobyeva OK, Kasparov EA. [Modern aspects of treatment of ophthalmic herper] Vestn. Ros. AMN. 2003;2:44-9. In Russian. 
  2. Gaidamaka TB. [Efficacy of penetrating and lamellar keratoplasty in recurrent herpetic keratitis] Oftalmol Zh; 2007:6(15-9). In Russian.  
  3. Ren Y, Wang H, Zheng Q, Tian P, Ren W, Jhanji V, Chen W. Long-Term Outcomes of Deep Anterir Lamellar Keratoplasty Treating Posterior Stroma-Implicated Herpetic Corneal Opacities. Cornea. 2016;35(3):299-304.
    Crossref   Pubmed
  4. Trufanov SV, Malozhen SA, Zaĭtsev AV.  Lamellar minikeratoplasty for reccurent herpes keratitis in the late post-LASIK period. Vestn Oftalmol. 2014;130(5):60-3.