https://doi.org/10.31288/oftalmolzh201565053

Original device and approaches to the study of temperature distribution in various eye segments (experimental study)

L.I. Anatychuk 1, Academician NAS  of Ukraine

N.V. Pasyechnikova 2, Doctor of Medical Sciences, Professor, Associate Member of NAMS of Ukraine 

O.S. Zadorozhnyy 2, PhD in Medical Sciences, 

R.E. Nazaretyan 1, ophthalmologist, 

V.V. Myrnenko 2, Head of Organizational and Methodological  Department, 

R.R. Kobylyanskyi 2, PhD in Physical and Mathematical Sciences, 

N.V. Gavrilyuk 2

1 Institute of Thermoelectricity of National Academy of Sciences and Ministry of Education and Science of Ukraine, Chernovtsy, Ukraine

2 SI “The Filatov Institute of Eye Diseases and Tissue Therapy of NAMS of Ukraine”, Odessa, Ukraine.

E-mail: rudolph84@mail.ru

Keywords: thermoelectric device, temperature, thermocouple, rabbit eye.

Introduction. Today the question of temperature distribution in various eye segments of human and animals remains understudied.

Objective. To design the device for measuring intraocular temperature and to study in the experiment the principle of temperature distribution in various segments of rabbit eye. 

Material and methods. Experiment was carried out on 11 rabbits (22 eyes). For temperature measurement the thermoelectric device was designed, which consists of temperature registration module, measure probes of 0.7 mm in diameter and computer with software.

Results. Under ambient temperature 23.8°C, the temperature of various eye segments was the following: posterior fornix of conjunctiva ? 37.41°C; anterior fornix of conjunctiva ? 36.82оС; cornea surface ? 34.41оС; ocular anterior chamber ? 35.97оС; anterior part of vitreous ? 36.96оС; of middle part of vitreous ? 37.40оС; back part of vitreous ? 37.50оС; of retina/ vascular membrane ? 37.64оС; subtenon area ? 37.78оС. Temperature difference of cornea external surface and ocular anterior chamber was 1.56оС, and of cornea external surface and retina was 3.23оС.

Conclusion. Thermoelectric device, which helps to make measurements in various eye segments, was designed. Due to this device the temperature distribution in rabbit eye was studied in vivo.

 

References

1. Shamshad MA, Amitava AK, Ahmad I, Wahab S. Changes in central retinal artery blood flow after ocular warming and cooling in healthy subjects. Indian J Ophthalmol. 2010;58:189-94.
   Crossref   Pubmed
2. Lazarenko VI, Chanchikov GF, Kornilovskiy IM, Gaydabura VG. [Influence of moderate local hypothermia to haemo- and hydrodynamic indices of healthy eyes]. Oftalmol Zh. 1976;6:419-422. Russian.
3. Lazarenko VI, Petrova SV, Kornilovskiy IM, Gaydabura VG. [Influence of moderate local hypothermia to carbohydrate metabolism  of healthy eye in the experiment]. Oftalmol Zh. 1977;3:227-230. Russian.
4. Purslow C, Wolffsohn J. Ocular surface temperature: a review. Eye and Contact Lens, 2005;31:117-123.
   Crossref
5. May DR, Freedland RJ. Ocular hypothermia: anterior chamber perfusion. British Journal of Ophthalmology. 1983;67:808-813.
   Crossref
6. Buiko AS, Elagina VA, Mazokhin SI, Logay IM, Shitova IY. [Local SHF-hypothermia in combination treatment of malignant tumors of eyelid and eyepit]. Med. Radiologia. 1988;8:7-11. Russian.
7. Schwartz B, Feller MR. Temperature gradients in the rabbit eye. Investigative Ophthalmology. 1962;1(4):513-521.
8. Fatt I, Forester JF. Errors in eye tissue temperature measurements when using a metallic probe. Exp. Eye Res. 1972;14:270-276.
   Crossref