Oftalmol Zh.2015;1:75-78


Neuroprotective therapy in compressive traumatic optic neuropathy caused by fracture of the orbit bone 

N. M. Moiseenko, G. M. Leskiv 

Ivano-Frankivsk National Medical University; Rohatyn clinical hospital; Ivano-Frankovsk (Ukraine)

Introduction. Common cause of irreversible visual loss due to optic nerve atrophy is its traumatic entrapment. 

Objective. To increase the effectiveness of the treatment of traumatic optic neuropathy compression caused by the orbit fractures by using neuroprotective therapy. 

Material and methods. We have examined 6 patients with compressive lesions of the optic nerve. The most effective was the use of neuroprotective support before, during surgery and in the early postoperative period. So the patient, despite the severe multiple fracture of the lower and outer walls of the orbit with displacement, the crack in the orbit apex, low preoperative visual acuity (within 0.04 on the affected side and 0.6 on the opposite side), visual acuity in both eyes is 1.0 in 3 months after injury. Consequently, the use of neuroprotective support for compression of traumatic optic neuropathy caused by fractures of the orbit will help protect the optic nerve from the possibility of re-injury, and improvement of the ways to use it will improve the effectiveness of the treatment on the whole. 

Key words: Traumatic entrapment of the optic nerve, neuroprotective therapy, methyl prednisolon


1. Серова Н. К. Синдромы поражения зрительного анализатора (нейрохирургические аспекты) / Н. К. Серова // Актуальные вопросы нейроофтальмологии : IX науч.-практич. нейроофтальмологическая конференція : тезисы докл. — М., 2007. — С. 123-127.

2. Andrew G. Lee. Clinical Pathways in Neuro-Ophthalmology An Evidence-Based Approach, Second Edition / [Andrew G. Lee, Paul W. Brazis]. — New-York-Stuttgart: Thieme, 2003. — 486 p.

3. Dojcinovic I. O 8-8 complications majeures d'un traumatisme maxillo-facial: neuropathie optique traumatique et mucormycose / Dojcinovic I., Broome M., Richter M. // Revue de Stomatologie et de Chirurgie Maxillo-Faciale. — 2005. — Vol 106 — № SUP4. — P. 33-33.


4. Kountakis S.E. Endoscopic optic nerve decompression for traumatic blindness. / [Kountakis S.E., Maillard A.A., El-Harizi S.M., Longhini L., Urso R.G.] // Otolaryngol. Head Neck Surg. — 2000. — Vol. 123 — P. 34-37.

Crossref   PubMed  

5. Nau H.E, Gerhard L. Optic nerve trauma: Clinical, electrophysiological and histological remarks. / [Nau H.E, Gerhard L., Foerster M.] // Acta. Neurochir. — Wien, 1987. — 22p.

Crossref   PubMed

6. Rajiniganth M. G. Traumatic Optic Neuropathy. Visual Outcome Following Combined Therapy Protocol [Ashley Anne Weaver. Computational Modeling of Eye Trauma for differentorbit Anthropometries and Different Projectile Impacts.: Thesis … Master of science. Biomedical Engineering / Ashley Anne Weaver ; Virginia tech — wake forest university school of biomedical engineering & sciences. — Winston-Salem, North Carolina. — 2010. — 96 р.;

7. Rajiniganth M. G., Ashok K. Gupta, Amod Gupta, Jayapalli Rajiv Bapuraj] / Arch. Otolaryngol., head., neck surg. –Vol.129. — 2003. — P. 1203-1206. 

Crossref  PubMed