Oftalmol Zh.2013;4:40-44


The effect of intravitreal ranibizumab injection on eye hemodynamic in patients with diabetic cystoid macular edema study

Ponomarchuk V. S., Khramenko N. I., Rozanova Z. A., Maher Alzein

SI «Filatov Institute of Eye Diseases and Tissue Therapy of National Academy of Medical Science», Odessa, Ukraine

Key words: diabetic macular edema, rheoophthalmography

31 patient (41 eyes) with cystoid macular edema were divided into 2groups by age (group 1—40—59years, 16 patients, 19 eyes and group 2 — more than 60 years, 15 patients, 22 eyes) and rheographic factors RQ and a/T before intravitreal ranibizumab injection(IRI) and 1, 3, 6 months and 1 year after were investigated and compared with age norm. Repeating courses of metabolic and vascular protecting therapy were administrated immediately after IRI and 3, 6 months subsequently. During a year 1 IRI administrated on 3 eyes (7,3 %), 2 IRI on 10 eyes (24,4 %), and 3 IRI on 28 eyes (68,3 %).

Rheographic factors RQ and a/T tended to decrease before treatment, 1 months after in group 1, and 3 months after in group 2 factor RQ was approaching the normal and remained at that level through one year follow-up, no statistically sig-nificant differences from the age norm was found. IRI has insignificant effect on choroidal blood supply on patients with cystoid macular edema.


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