Oftalmol Zh.2013;4:50-55


Correlation between progression of nonproliferative diabetic retinopathy and high level of glycated hemoglobin in patients with diabetes mellitus type II

P. A. Bezdetko, Y N. Ilyina, S. M. Ajaj

Kharkiv national medical university

e-mail: Iliyna@list.ru

Key words: glycosylated hemoglobin, diabetic retinopathy, correlation coefficient.

40 patients with nonproliferative diabetic retinopathy (DR) in diabetes mellitus type II and decompensated (after 7.5 %) level of glycosylated hemoglobin were observed within one year. The correlation between signs of DR and level of glycosylated hemoglobin were determined. Research included: static perimetry, optical coherent tomography, fluorescein angiography. As a result, significant correlation was established between the level of glycosylated hemoglobin and mean deviation MD (r=0,36; r=0,49), quantity of local defects in the visual field (r=0,35; r=0,47), thickness and volume of the central retina (r=0,34; r=0,49 and r=0,47; r=0,60), p<0,05 respectively in stage A and stage B of nonproliferative diabetic retinopathy (NPDR). NPDR was progressed from stage A to stage C within one year. Direct correlation was increased in 1.4 times during the year.


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