https://doi.org/10.31288/oftalmolzh201337578
Comparison of the influence of the dexamethasone diclofenac local application on the course of epithelization of the cornea after burn
S. A. Yakimenko, P. O. Kostenko
The Filatov Institute of Eye diseases and Tissue Therapy of National Medical Sciences Academy, Odessa
Key words: eye burn, dicloafenac, dexamethasone
The treatment of the inflammatory reaction, which develops as a result of the eye burn damage, is a very complex and unsolved problem.
Purpose of the study. To study the influence of instillations of steroid and nonsteroid preparations on the course of postburn reparative process in the cornea in the experiment.
Material and methods. The chemical burns of the cornea (3B cm) were modeled in 10 eyes of experimental animals
Conclusion. It was shown that the groups where instillations of 0.1 % solution of diclofenac Clodifen and 0.1 % solution of dexamethasone were given were not noted negative effect of both steroid and nonsteroid preparations on the course of the postburn reparative process in the cornea in comparison with the control one. The results obtained allow to recommend these preparations for treatment of the eye burns from the first day after under the condition of a constant control of the cornea state.
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