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http://doi.org/10.31288/oftalmolzh201136064

THE STUDY OF THE ENZYME ACTIVITY OF THE ANTIOXIDANT EYE TISSUE SYSTEM IN MODEL¬ING CATARACT IN ANIMALS WITH STREPTOZOCIN DIABETES

N. F. Leus, Ben Abdallakh Anis, Yu. A. Zhuravok

Odessa, Ukraine

The activity of the antioxidant system enzymes of the eye tissues is studied in modeling of cataract in animals with streptozotocin diabetes.

The experimental studies were conducted on 49 rabbits. The determination of the activity of the enzymes of superoxidedismutase, catalase and glutathionperoxidase was made in the tissues of the lens and humor.

The noticeable decrease of the indices of the enzyme activity of the antioxidant system in the humor was noted in modeling of light cataract in animals with diabetes. The degree of decrease in superoxidedismutase in diabetic animals and in light exposure was 48.5 % in comparison with the norm and 84 % in comparison with cataract animals without diabetes.

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