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http://doi.org/10.31288/oftalmolzh201132530

DETERMINATION OF FUNCTIONAL AND ORGANIC CHANGES IN THE HEMATORETINAL BARRIER WITH DIABETIC RETINOPATHY WITH THE AID OF VITREAL FLUOROMETRY

V. A. Naumenko, N. N. Kushnir

Odessa, Dnepropetrovsk, Ukraine

There was revealed a direct dependence of the state of the hematoretinal barrier (HRB) on the stage of diabetic retinopathy (DRP) according to the data of vitreal fluorometry. The level of vitreal fluorescence (VF) on the 5th minute after introduction of fluorescein reflects the dependence of the dye flow through HRB in the vitreous body on the degree of the manifestation of organic changes in the vascular wall. The level of VF on the 30th minute of the experiment characterizes functional possibilities of HRB for this specific time. Increase in the level of VF both on the 5th and on the 30th minutes of the experiment in the developed stages of DRP is caused by the progression of both functional and organic changes of HRB.

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