Adaptive myopia. Part 1. Actuating mechanisms of optic axis growth in the incremental retinal defocus theory
1Koshits I.N., Director of Petercom-Networks
2Svetlova O.V., Dr. Sc. (Med.), Prof.
3Guseva M.G., ophthalmologist
4Balashevich L.I., Dr. Sc. (Med.), Prof.
5Makarov F.N., Dr. Sc. (Med.), Prof.
6Egemberdiev M.B., Cand. Sc. (Med.)
1Petercom-Networks / Management Systems Consulting Group Cl. corp., St. Petersburg, Russia;
2I. Mechnikov Northwestern State Medical University, St. Petersburg, Russia;
3Diagnostic municipal Center «Vodokanal Spb.», St. Petersburg, Russia;
4S. Fyodorov Eye Microsurgery Federal State Institution, St. Petersburg branch, Russia;
5Pavlov Institute of Physiology Russian Academy of Sciences, St. Petersburg, Russia.
6United Hospital of the «Chuya» District, Department of Ophthalmology, Bishkek, Kyrgyzstan
The modern theory of acquired myopia (the theory of retinal defocus) is being considered against the backdrop of the global pandemic forecast: about 5 billion by 2050 year. The inconsistency of tincremental retinal defocus theory in part of the proposed executive mechanisms has been revealed. Until the regulations for visual work are absent, the issues of video ecology and total prevention of acquired myopia should take the first place in the fight against the myopia pandemic.
Key words: adaptation, acquired myopia, defocus theory, video ecology, visual performance, control mechanisms of accommodation and axial length
1. Avetisov ES. [Myopia]. M.: Meditsina; 1986. 216 p. Russian.
2. Avetisov SE. [Myopia as manifestation of body adaptive reaction]. XIX Intern. Ophthalm. Congress “White Nights”. SPb.; 2013. 132-9. Russian.
3. Avetisov ES, Kovalevskii EI, Khvatova AV. [Guidance in pediatric ophthalmology]. M.: Meditsina; 1987. 354p. Russian.
4. Avetisov ES, Rozenblium IuZ. Ophthalmological issues in cybernetic aspect. M.: Meditsina; 1973. 86 p. Russian.
5. Avetisov ES, Rozemblium IuZ. What myopia optic correction should be like? (To discussion results). Oftalmol Zh. 1974;3:72-8. Russian.
6. Avetisov ES. [Myopia]. M.: Meditsina; 1999. 288 p. Russian.
7. Accomodation. [Guidance for physicians]. Ed. Katargina LA. M.: Aprel; 2012. 136p. Russian.
8. Ananin VF. [Accommodation and myopia]. M.: Biomedinform; 1992. 73 p. Russian.
9. Ananin VF, Ananin VV. [Eye and pharmacology]. M.: Biomedinform; 1994. 82p. Russian.
10. Andreeva LD. [Structural changes in the sclera in myopia and emmetropia]. Thesis for Cand. Sc. (Biol.). M.; 1981. 171 p. Russian.
11. Babanov SA. [Professional eye diseases: optimization of diagnostic and treatment procedures]. RMJ. Clinical ophthalomology. 2015;2:89-94. Russian.
12. Balashevich LI. Dynamics of visual acuity recovery after intensive short-term light exposures on the eye in norm and in some diseases of the yellow spot: author’s thesis for Cand. Sc. (Med.). L.: VMA; 1974. 17p. Russian.
13. Boiko EV, Volkov VV, Kolesnikova LN, Shelepin IuE. [Studying mechanisms of altered vision in a human’s work with videomaterials]. Sensornyie sistemy. 1989;3(3):307-13. Russian.
14. Volkov VV. [On accommodation of the eye]. Okulist. 2003;6(46):6-7. Russian.
15. Volkov VV, Gorban AI, Dzhaliashvili OA. [Clinical visometry and refractometry]. L.:Meditsina; 1976. 256p. Russian.
16. Volkov VV, Kolesnikova LI. [Accommodation and refraction according to study materials of cobalt glass]. Oftalmol Zh. 1973;3:172-6. Russian.
17. Volkov VV, Luizov AV, Ovchinnikov BV, Travnikova NP. [Ergonimics of visual activity of human]. L.: Mashinostroieniie; 1989. 156p. Russian.
18. Volkov VV, Kotliar KE, Koshits IN, Svetlova OV, Smolnikov BA. [Biochemical features of interaction of accommodative and drainage systems of the eye in norm and in contusion lens subluxation]. Vestn. Oftalmol. 1997;3:5-7. Russian.
19. Volkov VV, Strakhov VV. [On accommodation in distance and in glasses preserving the possibility of its active use with myopic eye for distance vision]. Vestn. Oftalmol. 2007;2:32-7. Russian.
20. Viazovskii IA. [Device for objective assessment of visual acuity]. Oftalmol Zh. 1962;7:391-5. Russian.
21. Galkin NN. [Manual for lens fitting]. 2nd edition. Volkov VV, the editor. Medgiz LO; 1980. 185 p. Russian.
22. Guseva MG, Svetlova OV, Koshits IN. [On a choice of physiologically-based rational correction for stabilization of acquired myopia in children]. Glaz. 2012;1:12-7. Russian.
23. Dashevskii AI. [Pseudomyopia]. M.; 1973. 163p. Russian.
24. Dashevskii AI. [On correction of main elements in anatomic and optic system of the eye]. Oftalmol Zh. 1983;4:209-13. Russian.
25. Deinego VN, Kaptsov VA, Balashevich LI, Svetlova OV, Makarov FN, Guseva MG, Koshits IN. [Prevention of ocular diseases in children and teenager in classrooms with led light sources of the first generation. Analytical review]. Ross. Detsk. Oftalm. 2016;2:57-72. Russian.
26. Dobrovolskii VI. [On various accommodation-influenced changes of astigmatism]. Voienno-meditsinskii zhurnal. 1868;9 (103):34-44. Russian.
27. Zykov LI, Kulikov SM, Lvov LV, Manachinskii AN, Smyshliaiev SP, Sukharev SA, Shkapa AF. [Experimental model of the eye for intraocular lens testing and demonstrating. Biomechanics of the eye- 2005: proceedings of scientific conference]. M.: MNIIGB im. Gelmgoltsa; 2005. 186-190. Russian.
28. Иванов А. А. Рефракция глаз у детей в первые месяцы жизни: дис. ... – СПб., 1898.
29. Kornilovskii IM. New energy-saving hydrohemodynamic theory of accommodation. Refraktsionnaia khirurgiia i oftalmologiia. 2010;3(10):16-22. Russian.
30. Kornushina TA. Physiological mechanisms of development of visual fatigue and overstress while performing visually stressing work. Vestn Oftalmol. 2000;4:33-9. Russian.
31. Koshits IN, Makarov FN, Svetlova OV, Zaseeva MV, Kotliar KE. [Biochemical features of ciliary muscle regulation of accommodation and aqueous humor outflow in guided refractive and pharmacological interventions. Biomechanics of the eye- 2005: proceedings of scientific conference]. M.: MNIIGB im. Gelmgoltsa; 2005. 20-4. Russian.
32. Koshits IN, Svetlova OV. [Glossary – Functionary: accommodation mechanisms]. REFRACTION 2008: Proceedings of ophthalmol. conference. Samara; 2008. 54-62. (www.organum — visus.com / Biomechanics of the Eye). Russian.
33. Koshits IN, Svetlova OV. [Discussion on acquired myopia]. Oftalmol Zh. 2012;6:111-22. Russian.
34. Koshits IN, Svetlova OV. Formation of the adequate length of eye and the metabolic theory of the pathogenesis of acquired myopia. Oftalmol Zh. 2011;5:4-23. Russian.
35. Koshits IN, Svetlova OV. [Ontogenesis of formation of necessary length of the eye and metabolic theory of myopia pathogenesis]. Biomechanics of the eye- 2007: proceedings of scientific conference]. M.: MNIIGB im. Gelmgoltsa; 2007. 13-33.
36. Koshits IN, Svetlova OV. [Development of Helmholtz's theory of accommodation according to studies of additional accommodation mechanisms]. Vestnik RAMN. 2003;2:3-12. Russian.
37. Koshits IN, Svetlova OV. [Modern visions of Helmholtz's theory of accommodation: work-book]. SPb: ID SPbMAPO; 2002. 30p. Russian.
38. Koshits IN, Svetlova OV, Guseva MV, Makarov FN. [Priority directions in the fight against acquired myopia: theory and practice]. Glaz. 2013;6(82):12-7. Russian.
39. Koshits IN, Svetlova OV, Makarov FN. [Modern concepts about executive mechanisms of accommodation and Helmholtz theory. Part 1. Physiological and biomechanical peculiar properties of the accommodation system]. Glaz. 2012;2(84):11-20. Russian.
40. Koshits IN, Svetlova OV, Makarov FN, Guseva MV. М. В. [The physiological and biomechanical postulates of the new theories of accommodation]. Glaz. 2013. 3(82); 15-21. Russian.
41. Koshits IN, Svetlova OV. [Ontogenesis of formation of necessary length of the eye in childhood and metabolic theory of myopia pathogenesis]. Glaz. 2007;6(58):16-31. Russian.
42. Koshits IN, Svetlova OV, Gorban AI. [Functioning of executive mechanisms of accommodation and development of Helmholtz's theory of accommodation. Normal physiology of the eye: monograph]. SPb.: Izd-vo SZGMU im. I.I. Mechnikova; 2004. 180p. Russian.
43. Koshits IN, Svetlova OV, Makarov FN. [Metabolic theory of progressive myopia]. Proceedings of XII Ukrainian Congress of ophthalmologists. Odessa;2010:257. Russian.
44. Koshits IN, Svetlova OV, Makarov FN. [Acquired myopia as a classic case of prevalence of accommodation over outflow]. [Binocular and oculormotor disorders: proceedings of scientific practical conference in Helmholtz Moscow Research Institute]. M.;2007:135-7. Russian.
45. Koshits IN, Svetlova OV, Makarov FN, Guseva MG. [Rational correction is an effective method for stabilizing acquired myopia]. Proceedings of IX All-Russian scientific practical conference “Fedorov Memorial Lectures”. M.:2011:104-6. Russian.
46. Krasilnikov NN, Krasilnikova OI, Shelepin IuE. [A model of formation of frequency and contrast characteristic of visual system in dependence on light intensity of the retina]. Sensornyie sistemy. 1997;3(11):333-9. Russian.
47. Lagace JP. [Incremental Retinal Defocus Theory and Progressive Myopia.]. Vestnik optometrii. 2011;1:48-57. Russian.
48. Lialin AN, Blinova OV, Korepanov AV. [Retinal defocus and vergence and accommodation stresses as regulatory mechanisms for refractogenesis]. Sovremennyie tekhnologii v oftalmologii. 2015;2:139-46. Russian.
49. [International anatomic nomenclature (with the official list of Russian equivalents)]. 2nd Edition. M.: Meditsina; 2013. 234p. Russian.
50. Muravieva SV, Pronin SV, Shelepin IuE. [Contrast sensitivity of the human visual system]. Eksperimentalnaia psikhologiia. 2010;3(3):5-20. Russian.
51. Nikolaieva TE. [To a comparative structural inferiority of accommodative muscles and sclera in moderate severe myopia. Myopia: collection of papers of scientific practical conference in Helmholtz Moscow Research Institute]. M.; 1974. 49-51. Russian.
52. Pavlov NN, Danilova MV, Shelepin IuE. [Optimization of a human-display system]. Tekhnika kino I televideniia. 1989;11:8-14. Russian.
53. Pivovarov NN, Surkova EN. [Accommodation and presbyopia in the view of new hypotheses (disputing issues).] Refraktsiia khirurgii I oftalmologii. 2010;4:4-10. Russian.
54. Pospelov VI, Petrushenko OV. [Absolute accommodation in various refraction of the eye in children. Current issues of clinic, diagnostics and treatment in ophthalmology: proceedings]. Barnaul-Belokurikha: OOO “Akimirika”; 2009:121-24. Russian.
55. Radzikhovskii BL. [Astigmatism of the human eye]. M.: Meditsina; 1969. 194p. Russian.
56. Radzikhovskii BA. Myopia. M.: Medgiz; 1963. 187p. Russian.
57. Rozenblium IuZ. [Refraction, accommodation and vision. In a paper collection “Clinical physiology of vision”]. M.: Izd. AO “Rusoved”; 1993: 180-198. Russian.
58. Rozenblium IuZ, Koshits IN, Svetlova OV, Sheludchenko VM. [Accomodation at a young age. Norm and pathology]. Vestnik RAMN. 2003;5(3):10-5. Russian.
59. Svetlova OV, Koshits IN. [Biochemical aspects of possible common causes of inherited and acquired myopia. Myopia, disorders of refraction, accommodation, and oculormotor system: proceedings]. M.:MNII im. Gelmgoltsa; 2001: 77-78. Russian.
60. Svetlova OV, Koshits IN. [Interaction of main intraocular fluid outflow pathways with accommodation mechanism: textbook]. SPb.: ID SPbMAPO; 2002. 50p. Russian.
61. Svetlova OV, Koshits IN. [Classification and interaction of accommodation mechanisms in the human eye]. Biomechanics of the eye – 2000: proceedings. M.: MNII im. Gelmgoltsa; 2002: 117–119. Russian.
62. Svetlova OV. [Regulatory biomechanism of uveascleral outflow in the human eye]. Ophthalmology between two ages: proceedings. SPb: VMA; 2001: 207-208. Russian.
63. Svetlova OV. [Functional peculiarities of the interaction between the sclera, accommodation and drainage systems of the eye in glaucoma and myopia pathology]. Author’s thesis for Dr Sc (Med). M.; 2010. 55p. Russian.
64. Svetlova OV, Koshits IN., Drozdova GA. [Interaction of aqueous humor outflow mechanisms and accommodation in myopia and glaucoma. Pathological physiology of the eye: monograph]. SPb.: Izd-vo SZGMU im. I.I. Mechnikova; 2014. 164p. Russian.
65. Svetlova OV, Koshits IN., Kugleev AA. [Physiological peculiarities of ciliary muscle in guided refractive interventions]. VII Congress of ophthalmologists of Russia: proceedings. Moscow; 2000: 287. Russian.
66. Sergiienko NM. [Theory of accommodation: whether a Helmholts theory should be corrected?] Oftalmol Zh. 2000;2:81-2. Russian.
67. Serdiuchenko VI, Viazovskii IA. [Studying accommodation in different meridians of the eye and modified treatment of its disorders in hypermetropia amblyopia]. Biomechanics of the eye – 2004: proceedings. M.: MNII im. Gelmgoltsa; 2004: 33-37. Russian.
68. Somov EE. [Ophthalmoergonomics of operative activity of air staff]. SPb.: Politekhnika; 1992. 176p. Russian. Сомов
69. Sorokin GA, Avetisov ES. [On a new hypothesis of myopia origin. In a book “Proceedings of scientific conference, dedicated to 90th anniversary of V.Filatov”]. Kiev; 1965: 34-9. Russian.
70. Sorokin GA. [Studying a professional risk in visual stress]. Meditsina truda I promyshlennaia ekologiia. 2009;4:30-5. Russian.
71. Stepanova LV. [Transport functions of lens epithelium (biophysical aspects)]: author’s thesis for Cand Sc (Biol). Krasnoiarsk: KMA; 2005. 26p. Russian.
72. Tarutta EP, Milash SV, Tarasova NA, Epishina MV, Adzhemian NA. [Induced peripheral defocus and the shape of the posterior eye pole in orthokeratological myopia correction]. Ross Oftalmol Zhurn. 2015;3:52-6. Russian.
73. Tarutta EP, Khodzhabekian NV, Filinova OB. [Modern ideas of a role of accommodation in refractogenesis. In a book “Accommodation: guidance for physicians” edited by Katargina LA. M.]: Aprel;2012:35-9.
74. Tron EZh. [Changeability of elements of optic system of the eye and its meaning for clinic]. L.; 1947. 354p. Russian.
75. [Federal clinic recommendations. Diagnostics and treatment of myopia in children. Interregional public organization “Association of ophthalmologists”]. Moscow; 2013. 49p. Russian.
76. [Federal clinic recommendations. Diagnostics and treatment of myopia in children]. Ross. Pediatricheskaia Oftalmologiia. 2014;2:49-62. Russian.
77. Feigin AA. [Professional ophthalmopathy: clinics, diagnostics, rehabilitation, prevention]. Thesis for Dr Sc (Med). 2006. 199p. Russian.
78. Filinova OB. [Studying the effect of persistent mild myopia defocusing of image on the refraction dynamics, binocular functions and growth of the eye in children: author’s thesis for Cand Sc (Med)]. M.; 2009. 26p. Russian.
79. Khokhlova TV, Panova IG. [Formation of accommodationin in fresh-water turtles emys orbicularis L]. Sensornyie sistemy. 2006;4(20):300-8. Russian.
80. Shapalov S, Shelepin IuE, Miliavskaia TI et al. [Guidance on diagnostics, expertise, recovery of visual capacity in persons of air and dispatcher staff of civilian aviation]. M.: Vozdushnyi transport; 1990. 104p. Russian.
81. Shapovalov SL. [Clinical and physiological peculiarities of absolute accommodation of the human eyes and methods of its studying; author’s thesis for Dr Sc (Med)]. M. M.; 1977. 29 p. Russian.
82. Shapovalov SL, Bursov IV. [Biomechanics of Bagolini and Maddox tests]. Biomechanics of the eye – 2009: proceedings. M.: MNII im. Gelmgoltsa; 2009: 46-49. Russian.
83. Shapovalov SL, Miliavskaia TI, Ignatiiev SA. [Accommodation of the eye and its desorders: monograph]. M.: MIK; 2011. 183p. Russian.
84. Shapovalov SL, Miliavskaia TI, Ignatiiev SA. [Main forms of asthenopia]. M.: MIK; 2012. 287p. Russian.
85. Shapovalov SL, Miliavskaia TI, Ignatiiev SA. [Formation and course of myopia in adults]. M.: MIK; 2012. 199p. Russian.
86. Boyer MM, Poulsen GL, Nork TM. Relative contributions of the neurosensory retina and retinal pigment epithelium to macular hypofluorescence. Arch Ophthalmol. 2000;Jan;118(1):27-31.
87. Brien A Holden еt al, 2016. American Academy of Ophthalmology; www.aaojournal.org.
88. Hung GK, Ciuffreda KJ. An incremental retinal defocus theory of the development of myopia. Comments on Theoretical Biology. 2003;8:511-38.
89. Hung GK, Ciuffreda KJ. Differential retinal-defocus magnitude during eye growth provides the appropriate direction signal. Med Sci Monit. 2000;6(4):791-5.
90. Hung GK, Ciuffreda KJ. Incremental retinal defocus theory predicts experimental effect of under-correction on myopic progression. JBO. 2004;3:59-63.