Oftalmol Zh.2015;3;13-17


New possibilities of substitution of the lipid layer of the tear film

Drozhzhyna G. I., Troichenko L. F. 

State Institution «The Filatov Institute of Eye Disease and Tissue Therapy of NAMS of the Ukraine»; Odessa (Ukraine)

The effect of eye drops «Eye-t® ectoine» containing 0.5 % solution of ectoine on clinical symptoms of dry eye syndrome was studied. 

Material i methods. The study was performed in 21 patients (39 eyes) with dry eye syndrome (DES) of moderate severity. Ectoine — natural bioregulator, stabilizes the lipid layer of the tear film, protects the epithelium of the cornea and conjunctiva of hyperosmolarity, moisten the surface of the eye, preventing dehydration. The preparation containing 0.5 % sodium ectoine instilled 6 times per day for 3 weeks. 

Results. The clinical results indicate that the use of eye drops «Eye-t® ectoine» in patients with DES increases the stability of the tear film, which results in a significant increase in the time tear firm break and is accompanied by a decrease in subjective symptoms and Ocular Surface Disease Index (OSDI)

Key words: dry eye, tear film, ectoine, treatment


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